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If the liver is injured or damaged, the liver cells spill these enzymes into the blood, raising the AST and ALT enzyme blood levels and signaling liver disease.
Other blood tests pertaining to the liver are measurements of some of the other enzymes found the liver.
Moreover, the precise levels of these liver enzyme tests do not correlate well with the extent of liver problems or the prognosis (outlook).
Thus, the exact levels of AST (SGOT) and ALT (SGPT) cannot be used to determine the degree of liver disease or predict the future prognosis for liver function.
It is important to clarify that ALT and AST levels do not reflect the function of the liver, even though in the medical community and in medical publications they commonly, and incorrectly, are referred to as liver function tests.
Even in conditions when AST and ALT are very elevated, the liver still may function properly.
These panels vary and may consist of AST, ALT and some or all of the tests listed above.
In addition, the normal panel values may vary somewhat, especially between adult men, women and children so viewing the "normal" ranges of test values is always recommended, and a thorough discussion with the physician is necessary.
The focus of this article is mainly on the most common liver enzymes, AST and ALT. It makes many of the chemicals required by the body to function normally, it breaks down and detoxifies substances in the body, and it also acts as a storage unit.When the liver is damaged from disease, medication, alcohol, or other factors., a person may have symptoms of liver disease such as The aminotransferases enzymes catalyze chemical reactions in which an amino group from one amino acid (amino acids are building blocks of proteins) is transferred from a donor molecule to a recipient molecule, hence, the names "aminotransferases."Medical terms can sometimes be confusing, as is the case with these enzymes because they have interchangeable names that commonly appear in both medical and non-medical articles.For example: AST (SGOT) is normally found in a variety of tissues including liver, heart, muscle, kidney, and the brain.Enzymes help to speed up (catalyze) routine and vital chemical reactions in the body.Among the most sensitive and widely used liver enzymes are the aminotransferases.